Education

PhD, Statistics , 2011/01 – 2015/12 , UW-Madison

MS, Probability Theory and Mathematical Statistics, 2007/09 – 2010/07, USTC

BS, Statistics, 2003/09 – 2007/07, USTC


Publications

Tian J, Keller MP, Broman AT, Kendziorski C, Yandell BS, Attie AD, Broman KW (2016) The dissection of expression quantitative trait locus hotspots. Genetics 202.4: 1563-1574. PubMed

Tian J, Keller MP, Oler AT, Rabaglia ME, Schueler KL, Stapleton DS, Broman AT, Zhao W, Kendziorski C, Yandell BS, Hagenbuch B, Broman KW, Attie AD (2015) Identification of the bile acid transporter Slco1a6 as a candidate gene that broadly affects gene expression in mouse pancreatic islets. Genetics 201:1253-1262. PubMed

Xiong L, Kuan P, Tian J, Keles S, Wang S (2015). Multivariate boosting for integrative analysis of high dimensional cancer genomic data. Cancer Informatics 2014: Suppl. 7 123-131. PubMed

Maenner MJ, Baker MW, Broman KW, Tian J, Barnes JK, Atkins A, McPherson E, Hong J, Brilliant MH, Mailick MR (2013) FMR1 CGG expansions: Prevalence and sex ratios. Am J Med Genet B Neuropsychiatr Genet 162:466-473. PubMed

Dissertation

Tian J (2015) Dissection and Fine-mapping of trans-eQTL hotspots. [PDF]


Software

R/qtlpvl

QTL mapping with multiple traits, including tests of pleiotropy vs. close linkage. Exploratory figures for dissection of trans-eQTL hotspot.

Source on github. View vignettes here.

R/qtlintv

R package for a simulation study on the behavior of QTL intervals in populations of Advanced Intercross Lines (AIL) and Diversity Outbred (DO) populations.

Source on github.

R/MaXact

Exact max-type Cochran-Armitage trend test. This package performs exact MAX3 or MAX2 tests for one-locus genetic association analysis and trend tests for dominant, recessive and additive models. It can also calculate approximate p-values, with a normal approximation.

Download from CRAN.


Presentations

Talks

Fine-mapping a trans-eQTL hotspot [PDF]
27th International Mammalian Genome Conference, Spain, September 17, 2013

Posters

Fine-mapping a trans-eQTL hotspot [PDF]
WARF Discovery Challenge 2014, Madison, WI, May 21, 2014


Contact

Email: jiant17@gmail.com