Jianan Tian Statistics PhD
Education
PhD, Statistics , 2011/01 – 2015/12 , UW-Madison
MS, Probability Theory and Mathematical Statistics, 2007/09 – 2010/07, USTC
BS, Statistics, 2003/09 – 2007/07, USTC
Publications
Tian J, Keller MP, Broman AT, Kendziorski C, Yandell BS, Attie AD, Broman KW (2016) The dissection of expression quantitative trait locus hotspots. Genetics 202.4: 1563-1574. PubMed
Tian J, Keller MP, Oler AT, Rabaglia ME, Schueler KL, Stapleton DS, Broman AT, Zhao W, Kendziorski C, Yandell BS, Hagenbuch B, Broman KW, Attie AD (2015) Identification of the bile acid transporter Slco1a6 as a candidate gene that broadly affects gene expression in mouse pancreatic islets. Genetics 201:1253-1262. PubMed
Xiong L, Kuan P, Tian J, Keles S, Wang S (2015). Multivariate boosting for integrative analysis of high dimensional cancer genomic data. Cancer Informatics 2014: Suppl. 7 123-131. PubMed
Maenner MJ, Baker MW, Broman KW, Tian J, Barnes JK, Atkins A, McPherson E, Hong J, Brilliant MH, Mailick MR (2013) FMR1 CGG expansions: Prevalence and sex ratios. Am J Med Genet B Neuropsychiatr Genet 162:466-473. PubMed
Dissertation
Tian J (2015) Dissection and Fine-mapping of trans-eQTL hotspots. [PDF]
Software
R/qtlpvl
QTL mapping with multiple traits, including tests of pleiotropy vs. close linkage. Exploratory figures for dissection of trans-eQTL hotspot.
Source on github. View vignettes here.
R/qtlintv
R package for a simulation study on the behavior of QTL intervals in populations of Advanced Intercross Lines (AIL) and Diversity Outbred (DO) populations.
Source on github.
R/MaXact
Exact max-type Cochran-Armitage trend test. This package performs exact MAX3 or MAX2 tests for one-locus genetic association analysis and trend tests for dominant, recessive and additive models. It can also calculate approximate p-values, with a normal approximation.
Download from CRAN.
Presentations
Talks
Fine-mapping a trans-eQTL hotspot [PDF]
27th International Mammalian Genome Conference, Spain, September 17, 2013
Posters
Fine-mapping a trans-eQTL hotspot [PDF]
WARF Discovery Challenge 2014, Madison, WI, May 21, 2014
Contact
Email: jiant17@gmail.com